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Malic acid, an organic dicarboxylic acid with two stereoisomeric forms, plays an important biochemical role in both the Calvin cycle and the citric acid cycle. It is used as a food additive and preservative, a therapeutic agent, and a dietary supplement.
The racemate of L-malic acid; reduces IFN-γ and TNF-α-induced CCL2 and ICAM expression in HaCaT human keratinocytes at 1 mM; inhibits epidermis and dermis thickening, as well as mast cell and eosinophil dermal infiltration in a mouse model of DNBC-induced atopic dermatitis at 10 mM
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective brain-penetrant and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease SRT in Fabry’s and Gaucher’s. purity: 99%
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(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid This product is intended for research and analytical applications (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form contributes to the pleasantly sour taste of fruits and is used as a food additive In Vitro It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L casei Furthermore deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid thus indicating that the cognate TC system regulates and is essential for the expression of ME Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose[1]
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Malic acid disodium hydrate is the disodium salt/hydrate form of malic acid used as a biochemical reagent, buffering agent, and additive for nutritional and assay applications. Typical purity is 98.0% and it is supplied in small pack sizes for laboratory use.
High purity: 98.0% for reliable analytical use.
Buffered salt form suitable for pH control in biochemical assays.
Available in small packs (500 mg) for method development and testing.
Water-soluble, white crystalline powder for easy formulation.
Includes datasheet and SDS for safe handling and storage.
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Malic acid disodium hydrate is the disodium salt hydrate form of malic acid intended for laboratory biochemical and buffering applications. It is a white to off-white powder with high water solubility and is supplied in small packs for laboratory use. The reagent is documented with storage and solubility data suited for assay workflows.
Disodium salt hydrate form of malic acid, useful as a buffer and biochemical reagent.
High purity: 98.0% suitable for analytical and assay work.
Water soluble: approximately 175 mg/mL (may require ultrasonic assistance).
Stable at room temperature when stored under nitrogen and away from moisture; extended storage in solvent at -20°C to -80°C.
Supplied in small laboratory pack sizes for convenient handling.
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(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid This product is intended for research and analytical applications (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form contributes to the pleasantly sour taste of fruits and is used as a food additive In Vitro It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L casei Furthermore deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid thus indicating that the cognate TC system regulates and is essential for the expression of ME Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose[1]
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More